Course Title: Biochemistry and Molecular Biology 1

Part A: Course Overview

Course Title: Biochemistry and Molecular Biology 1

Credit Points: 12.00

Course Code




Learning Mode

Teaching Period(s)


Bundoora Campus


160H Medical Sciences


Sem 1 2006,
Sem 1 2007,
Sem 1 2008,
Sem 1 2009


Bundoora Campus


160H Medical Sciences


Sem 1 2006,
Sem 1 2007,
Sem 1 2008,
Sem 1 2009,
Sem 1 2010,
Sem 1 2011,
Sem 1 2012,
Sem 1 2013,
Sem 1 2014,
Sem 1 2015,
Sem 1 2016


Bundoora Campus


173H School of Health and Biomed


Sem 1 2017

Course Coordinator: Dr Daniel A. Dias

Course Coordinator Phone: +61 3 9925 7071

Course Coordinator Email:

Course Coordinator Location: 203.03.32

Course Coordinator Availability: By appointment

Pre-requisite Courses and Assumed Knowledge and Capabilities

Prior Knowledge and Capabilities

Chemistry for Life Sciences (CHEM1240); Biology of the Cell (BIOL2272); Introduction to Medical Biochemistry (ONPS2423) or equivalent courses.

Course Description

  • Biochemistry and Molecular Biology 1 is a major component of the second year of the Laboratory Medicine (BP147), Biomedical Sciences (BP231) and Pharmaceutical Sciences (BP184) programs. It is designed to provide the student with an understanding of the disciplines of biochemistry and molecular biology, and their applications in the biochemistry laboratory and in research. The theory you will learn throughout the course will be intertwined and applied into a series of intensive laboratory practicals throughout the semester. Through the course you will gain an immersive laboratory experience covering concepts of experimental design, sample preparation and learning about current, state-of-the-art analytical techniques and platforms which are routinely used in clinical practise and research. You will develop the required employable attributes to either undertake professional practice or potential research endeavours.


Objectives/Learning Outcomes/Capability Development


This course contributes to the following Program Learning Outcomes for:

BP147 Bachelor of Biomedical Science (Laboratory Medicine)

PLO1. Knowledge capability: Understand appropriate and relevant, theoretical concepts of scientific knowledge with the ability to use and apply the knowledge in a wide range of problem solving, challenging and interpretative situations within the professional laboratory medicine discipline.

PLO2. Technical capability: Ability to apply a range of diagnostic technologies and methodologies relevant to the fields of Clinical Biochemistry, Haematology, Histopathology, Cytopathology or Microbiology.  These methodologies will identify pathological changes which deviate from the normal physiological range, use logical and systematic thinking to solve problems with diagnostic techniques and procedures, and apply high level analytical skills to the chosen area of clinical laboratory specialization.

PLO3. Professional work practices: Contribute to academic and professional work settings through responsible, self-managed, independent work, interpersonal skills which support constructive interactions with individuals and teams, and understand the ethical and legal framework that underpins the field of diagnostic pathology.


BP184 Bachelor of Biomedical Science (Pharmaceutical Sciences)

PLO1. Exhibiting depth and breadth of scientific knowledge: Develop a broad and coherent body of knowledge particularly in biochemistry, physiology, pharmacology and toxicology.

PLO2. Critically analyse and solve scientific problems: Adapt knowledge, concepts and skills to problem solve.


BP231 Bachelor of Biomedical Science

PLO2. Exhibit depth and breadth of scientific knowledge by: Demonstrating knowledge across disciplines contributing to biomedical science

PLO3. Critically analyse and solve scientific problems by: Gathering, synthesising and critically evaluating information from a range of sources; Designing and planning an investigation; Selecting and applying practical and/or theoretical techniques or tools in order to conduct an investigation and collecting, accurately recording, interpreting and drawing conclusions from scientific data.



On completion of this course you should be able to:

  1. Demonstrate an understanding of key concepts in biochemistry and molecular biology which form a comprehensive basis for further studies in the majors Biochemistry, Molecular Biology and Clinical Biochemistry.
  2. Demonstrate an understanding of key concepts in human biochemistry and molecular biology which form a basis for further studies in the following programs offered by the RMIT Science Engineering and Health College: Laboratory Medicine, Biomedical Sciences and Pharmaceutical Sciences.
  3. Prepare and analyse biological material and perform a series of biochemical investigations.
  4. Correlate, validate and interpret results of biochemical investigations.


Overview of Learning Activities


The learning activities of the course take place in the form of face-to-face lectures; laboratory based practical classes and tutorial sessions. The theory and practical components of the course are integrated throughout the teaching of the course. The practical program is designed to develop a high level of competence in the performance of a wide range of laboratory techniques;

A student-centered approach is adopted in the tutorial sessions and the self-directed learning activities of the course. These activities are conducted in parallel with the lecture program and consist of:

  • Targeted student-based discussions and;
  • Problem-solving of specific case studies and/or experimental data interpretation

Assessment activities are conducted as both formative and summative assessments. Formative as well as summative assessment occurs throughout the teaching in the laboratory classes of the course. Tutorials and self-directed learning activities;  Interactive, real-time quizzes at the end of selected lectures will provide continuous feedback to the student and lecturer regarding his/her understanding and level of performance in the interpretation of biochemical concepts and manipulation of biochemical data. Students will be able to access resources (eg. Lecture notes and recorded lectures, supplementary data) through the RMIT’s Blackboard Learning Management System which is the central forum used to communicate announcements and discuss questions with academics and peers.

Assessment activities are conducted as both formative and summative assessments. Formative as well as summative assessment occurs throughout the teaching in the laboratory classes of the course. You will undertake 3 hours of lectures per week (33 hours in total); 4 hours of tutorials consisting of self-directed learning; 30 hours of laboratory practical classes which are all face-to-face based. It is expected that you will carry out a total of 64 hours of independent study for this course throughout the semester.

Overview of Learning Resources


Learning resources in this course include text books, lecture notes (Powerpoint presentations), laboratory practical exercises, real-time quizzes, handouts and references on selected topics. The myRMIT site provides opportunities for students to independently access much of this material and use an asynchronous conference.

Overview of Assessment


☐This course has no hurdle requirements.

☒All hurdle requirements for this course are indicated clearly in the assessment regime that follows, against the relevant assessment task(s) and all have been approved by the College Deputy Pro Vice-Chancellor (Leaning & Teaching).

In order to satisfactorily complete the course, all students are required to undertake at least 80% of the practical work and to obtain an overall Pass for the Practical component of the course. Students must note that the laboratory sessions are available only at the specified times. The theoretical component of the course delivered in lectures will be assessed in a final semester examination, as well as two (2) Mid semester tests.

Assessment task



Assessment Task 1: Laboratory Practicals

CLOs 3 & 4


Assessment Task 2: Mid-Semester Test 1

CLOs 1 & 2


Assessment Task 3: Mid-Semester Test 2

CLOs 1 & 2


Assessment Task 4: Final Examination

CLOs 1, 2 & 4