Course Title: Molecular Genetics and Diagnostics

Part A: Course Overview

Course Title: Molecular Genetics and Diagnostics

Credit Points: 12.00


Terms

Course Code

Campus

Career

School

Learning Mode

Teaching Period(s)

ONPS2093

Bundoora Campus

Undergraduate

160H Medical Sciences

Face-to-Face

Sem 2 2006,
Sem 2 2007,
Sem 2 2008,
Sem 2 2009,
Sem 2 2010,
Sem 2 2011,
Sem 2 2012,
Sem 2 2013,
Sem 1 2014,
Sem 2 2014,
Sem 1 2015,
Sem 1 2016

ONPS2093

Bundoora Campus

Undergraduate

173H School of Health and Biomed

Face-to-Face

Sem 1 2017

ONPS2094

Bundoora Campus

Postgraduate

160H Medical Sciences

Face-to-Face

Sem 2 2006,
Sem 2 2007,
Sem 2 2008,
Sem 2 2009,
Sem 2 2010,
Sem 2 2011,
Sem 2 2012,
Sem 2 2013,
Sem 1 2014,
Sem 2 2014,
Sem 1 2015,
Sem 1 2016

ONPS2094

Bundoora Campus

Postgraduate

173H School of Health and Biomed

Face-to-Face

Sem 1 2017

Course Coordinator: Dr. Faith Kwa

Course Coordinator Phone: +61 3 9925 7773

Course Coordinator Email: faith.kwa@rmit.edu.au

Course Coordinator Location: 201.09.14D

Course Coordinator Availability: By appointment and via email


Pre-requisite Courses and Assumed Knowledge and Capabilities

Required prior study: BIOL1177 Biochemistry and Molecular Biology 1 and BIOL1181 Biochemistry and Molecular Biology 2 (or equivalent courses). Students who have not successfully completed the prerequisites must withdraw and will be withdrawn if they incorrectly enrol in this course


Course Description

This course will allow you to develop your theoretical and practical knowledge in the field of molecular genetics and diagnostics. In particular, the focus will be on genetic/genomic variation in disease and the impact of new technologies in this area. The syllabus is covered in a program of lectures, practical exercises, interactive tutorial workshops and computer based activities designed to promote active learning and facilitate the acquisition of knowledge in the area of molecular genetics and its applications in diagnostics and medical research.


Objectives/Learning Outcomes/Capability Development

This course contributes to the following Program Learning Outcomes for the programs below: 

BP147 Bachelor of Biomedical Sciences (Laboratory Medicine):

PLO 1.  Knowledge Capability 

PLO 2.  Technical Capability 

PLO 3.  Professional work practices 

PLO 6.  Research Capacity 

MC158 Master of Laboratory Medicine:

PLO 1.  Knowledge Capability

PLO 2.  Technical Capability

PLO 3.  Professional work practices

MC111 Master of Biotechnology:

PLO 1. Understanding Science

PLO 3. Application of Knowledge and Skills

PLO 5. Personal and Professional Responsibility

 


On completion of this course you should be able to:

  1. Describe the structure and organisation of genes, chromosomes and the human genome.
  2. Define the various mutations and genetic abnormalities which can result in genetic diseases.
  3. Relate modern DNA technology to the application of disease gene identification and analysis.
  4. Explain the effects of human genome variation and its effect on disease.
  5. Evaluate the role of current molecular techniques in diagnostic pathology testing.
  6. Perform a range a molecular genetic techniques and analyse the experimental results.

 


Overview of Learning Activities

The lectures in this course will provide students with comprehensive coverage of fundamental principles of the various topic areas. The practical program is designed to acquaint you with a number of technologies in the laboratory and in the use of bioinformatics software and genomic databases. The interactive tutorial workshops are designed to assist students in gaining a better understanding of how to use bioinformatics and molecular diagnostic/research tools, and provide formative feedback to students in an engaging way to promote active learning of course material. In this course, you are required to access independent learning materials on the RMIT Learning Management System.

Over the semester, students will participate and engage in lecture sessions, practical classes and interactive tutorial workshops.  Independent study will be required during the semester.

The total study hours for this course is 120 hours: 1) 40 comprising face-to-face lectures, interactive tutorial workshops and practical sessions; 2) 40 hours of online activities; and 3) 40 hours of self-directed study.


Overview of Learning Resources

You will be encouraged to read widely and to research the various topics using libraries and relevant web sites. In addition, lecture material, practical notes and relevant journal articles will be provided on BlackBoard.  You will be required to access genomic databases such as NCBI and Ensembl for bioinformatics activities.

 


Overview of Assessment

This course has no hurdle requirements.

Assessment Tasks: 

Assessment Task 1: Mid-semester test

Weighting 15%

This assessment task supports CLOs 1, 2 & 3

Assessment Task 2: Bioinformatics assignment

Weighting 15%

This assessment task supports CLOs 1, 3 & 4

Assessment 3: Interactive tutorial/workshop activities

Weighting 15%

This assessment task supports CLOs 1, 2, 3, 4 & 5

Assessment 4: Practical Report 

Weighting 15%

This assessment supports CLO 6

Assessment 5: Final Exam

Weighting 40%

This assessment supports CLOs 1, 2, 3 & 5