Course Title: Drug Delivery 4

Part A: Course Overview

Course Title: Drug Delivery 4

Credit Points: 12.00

Terms

Course Code

Campus

Career

School

Learning Mode

Teaching Period(s)

ONPS2442

Bundoora Campus

Undergraduate

160H Medical Sciences

Face-to-Face

 Sem 2 2013,
Sem 2 2014,
Sem 2 2015,
Sem 2 2016

ONPS2442

Bundoora Campus

Undergraduate

173H School of Health and Biomed

Face-to-Face

 Sem 2 2017

Course Coordinator: Dr Thilini Thrimawithana

Course Coordinator Phone: +61 3 9925 7125

Course Coordinator Email: thilini.thrimawithana@rmit.edu.au

Course Coordinator Location: 201.09.007


Pre-requisite Courses and Assumed Knowledge and Capabilities

None


Course Description

This course advances from the physicochemical principles considered in CHEM1258 and expands the practice of preparation of the extemporaneous compounding of pharmaceutical products introduced in CHEM1260 and CHEM1261.  The preparation of complex formulations including suppositories and non-pharmacopoeial gels is considered in detail, together with requisite documentation, labelling, packaging and counselling requirements.  More sophisticated formulations including sterile products, parenteral nutrition and cytotoxic formulations are considered in detail, and concepts of pharmaceutical quality control and good manufacturing practice considered.  The clinical performance of formulations is linked to pharmacokinetic parameters, especially release from the formulation.

Please note that if you take this course for a bachelor honours program, your overall mark in this course will be one of the course marks that will be used to calculate the weighted average mark (WAM) that will determine your award level.

This applies to students who commence enrolment in a bachelor honours program from 1 January 2016 onwards. See the WAM information web page for more information.(http://www1.rmit.edu.au/browse;ID=eyj5c0mo77631)


Objectives/Learning Outcomes/Capability Development

This course contributes to capability development in the following Domains of the National Competency Standards Framework for Pharmacists in Australia:

  • Professional and Ethical Practice (Domain 1)
  • Communication, collaboration and self-management (Domain 2)
  • Review and supply prescribed medicines (Domain 4)
  • Prepare pharmaceutical products (Domain 5)
  • Critical analysis, research and education (Domain 8)


Course Learning Outcomes

On successful completion of this course, you should be able to:

  1. Prepare complex formulations including non-pharmacopoeial formulations not described in the APF (the Australian Pharmaceutical Formulary and Handbook) to a standard suitable for administration to a patient including requisite labelling, packaging and the provision of advice to the patient.
  2. Investigate, evaluate and report the physical characteristics of formulations including release kinetics and relate these to quality control and preformulation requirements.
  3. Relate the application of quality control, quality assurance and the principles of good manufacturing practice to regulation in Australia and internationally
  4. Relate the formulation and preparation of cytotoxic medicines and sterile products to environmental control, risk assessment and the clinical outcome for the patient.
  5. Relate the formulation of specialised veterinary medicines to the treatment and prevention of disease in animals and the management of pest species
  6. Relate the physicochemical properties of protein/peptide drugs to the design and performance of specialised formulations.


Overview of Learning Activities

Key concepts will be explained in face-to-face lectures of the course integrated with further exploration in assessed laboratory and tutorial exercises.  Students are expected to supplement these activities with recommended readings and private study.

  1. Lectures
    Lectures are organised into learning modules and provide the theoretical basis required for the successful completion of tutorial classes and examinations.  Lectures may include active learning exercises in the Pharmacy Collaborative Learning Suites.
  2. Tutorials
    Tutorials provide the opportunity to work through example puzzles (both individual and group) in a guided environment.  Attendance at tutorials is mandatory unless formally excused on medical or compassionate grounds; tutorials may include summative assessments.
  3. Extemporaneous Compounding and Quality Control Practical Classes
    The extemporaneous compounding of medicines for an individual patient based upon a porescription is a fundamental skill of pharmacists practising in Australia.  Throughout the practical series you will be guided through new production processes meeting the legal and ethical responsibilities of the pharmacist.  In Drug Delivery 4, these skills will be extended to the quality control of medicines.
  4. Directed self-learning activities
    Self-learning activities include the review of lecture material and competion of sample questions and tutorial exercises, further reading recommended and reflecting upon your learning.  Our expectation is that a course should represent 10 hours of study per week, of which only half is in formal, teacher-guided classes.


Overview of Learning Resources

Extensive course materials are distributed online through myRMIT, these may include:

  • digitised readings,
  • lecture notes,
  • video recordings
  • links to external internet sites and
  • access to RMIT Library online and hardcopy resources.

Students should check myRMIT regularly for updated information and resources.  Students are advised to purchase the recommended textbook and should review materials available through the library.
 


Overview of Assessment

Your ability to demonstrate an understanding of the key concepts using appropriate terminology will be assessed in written and oral assessments.   

All hurdle requirements for this course are indicated clearly in the assessment regime that follows, against the relevant assessment task(s) and all have been approved by the College Deputy Pro Vice-Chancellor (Learning & Teaching).

Assessment Tasks:

Assessment Task 1: Mid-semester test(s)

Weighting 20%

This assessment task supports CLOs 1, 2, 3, 4, 5 & 6

Assessment Task 2: Practical assessments

Weighting 30%

This assessment task supports CLOs 1, 2 & 3

Final practical test is a hurdle requirement for this course.

Assessment Task 3: End of Course Exam

Weighting 50%

This assessment task supports CLOs 1, 2, 3, 4, 5 & 6