Course Title: Advanced Medical Imaging

Part A: Course Overview

Course Title: Advanced Medical Imaging

Credit Points: 12.00

Course Code




Learning Mode

Teaching Period(s)


City Campus


135H Applied Sciences


Sem 1 2015,
Sem 1 2016


City Campus


171H School of Science


Sem 1 2017

Course Coordinator: Dr Jeffrey Crosbie

Course Coordinator Phone: +61 3 9925 3556

Course Coordinator Email:

Course Coordinator Location: 14.06.10

Course Coordinator Availability: By Appointment

Pre-requisite Courses and Assumed Knowledge and Capabilities

The student is assumed to have a bachelor degree majoring in physics, or another discipline with appropriate experience.


Required prior study: PHYS2135 Medical Imaging Physics.


Assumed knowledge: You are assumed to have a thorough understanding of the interaction of radiation with matter (such as that provided by PHYS2125/PHYS2137), how radiation and other physical phenomena are employed for the purposes of medical imaging (e.g. PHYS2135), and practical experience with radiation measurement and instrumentation (eg PHYS2126) or similar university-level theoretical and practical physics courses which provide evidence of equivalent capabilities.

Course Description

This course forms a core component of the MC215 Master of Medical Physics program. It builds upon the fundamental concepts of the main imaging modalities studied in PHYS2135 - radiological, MR, ultrasound, and Nuclear Medicine imaging. The PHYS-2134 course is a face-to-face lecture course and students are expected to attend the lectures. The course covers topics on medical image processing, image analysis, and image synthesis (e.g. 3D visualization, and rendering). Contemporary advancements in medical imaging technology have brought with them an increasing level of complexity from implementation through to applications and the need for quality assurance. Physicists working in the field require a comprehensive understanding of these advanced imaging technologies in order to appreciate capabilities and limitations, evaluate equipment performance and assess risk. This course provides candidates for the Master of Medical Physics with an understanding of advanced imaging systems and their integration across the fields of diagnostic radiology, nuclear medicine and radiotherapy. This will include study of time-resolved ("4-dimensional") imaging, image-guided radiotherapy, and hybrid-modality imaging (e.g. PET/CT) together with topics such as image registration and its integration into treatment facilities and protocols. Emerging medical imaging modalities such as Phase Contrast Imaging are also explored during the course. Students will use freely available software packages such as ImageJ/Fiji during practical classes. Where possible, we will make site visits to clinics/hospitals to see advanced medical imaging modalities in daily use and to observe the role of the medical physicist and see how these advances improve patient healthcare. There will also be specialist lectures by external, imaging experts during the course.


Course Objectives:

  1. to extend your knowledge of the technical basis for advanced medical imaging systems and develop the skills to critically evaluate the performance and outputs of such systems;
  2. to explore mathematical topics in image processing and analysis such as: image enhancement, segmentation, interpolation, registration, transformations, and visualization;
  3. to develop a comprehensive understanding of the functionality of advanced medical imaging systems including time-resolved, hybrid and treatment-room-integrated

Objectives/Learning Outcomes/Capability Development

This course will contribute to the following program capabilities (refer Master of Medical Physics program guide):

PLO1 - Advanced and integrated understanding of the applications of physical processes to the diagnosis and treatment of disease, including an understanding of contemporary developments in professional practice.

PLO2 - Advanced understanding of the origins of radiation and its interactions with matter pertaining to the production and use of ionising radiation, with particular regard to the protection of people and environments.

PLO4 - Skills to investigate, analyse and interrogate scientific data to ensure quality control of complex technological systems and to diagnose causes of discrepancies.

PLO7 - Technical and research skills to design, implement and evaluate developments in diagnostic and therapeutic technology that influence professional practice and scholarship.

PLO8 - Demonstrate the application of knowledge and skills with creativity and initiative to new situations in professional practice in fields related to Medical and Health Physics.

PLO9 - Demonstrate the application of knowledge and skills with a high level of personal autonomy and accountability.

On successful  completion of this course you should be able to :


  1. Demonstrate a comprehensive knowledge of range of advanced medical imaging systems and their relative merits and advantages;
  2. Interpret the physical and quantitiative information that may be extracted from different imaging modalities and to critically evaluate the limitations of these instruments as measurement systems;
  3. Apply image processing techniques and understand the applied mathematics which underlies medical imaging and medical image processing;
  4. Discuss the merits of advanced imaging relative to patient benefit considering such factors as patient comfort, diagnosis and treatment time, workload, radiation exposure, risks ;
  5. Independently progress your own learning and have the skills to teach This includes being able to access and use a variety of learning materials and resources;
  6. Work as part of a team in tutorial and laboratory sessions;
  7. Present worked solutions to problems and write reports in a concise, clear, systematic and professional manner;
  8. Apply the concepts, terminology, conventions and calculations important in diagnostic medical imaging and be able to demonstrate these when answering tutorial and assignment

Overview of Learning Activities

The learning activities included in this course are:

  • attendance at lectures where syllabus material will be presented and explained, and the subject illustrated with demonstrations and examples;
  • completion of tutorial questions, quizzes and tests designed to give further practice in the application of theory, and to give feedback on your progress and understanding;
  • private study, working through the course as presented in classes and learning materials, and gaining practice at solving conceptual and numerical problems;
  • written assignments requiring an integrated understanding of the subject matter and review of contemporary research literature.

Total study hours

48 teacher-guided hours and approximately 72 student-directed hours

Overview of Learning Resources

You will be able to access course information, lecture notes and other learning materials through the ’myRMIT Studies’ web service (specifically Blackboard). Lists of relevant reference texts, resources in the library and freely accessible internet sites will be provided in the lecture notes and during the classes. A number of freely available software packages (e.g. ImageJ and Fiji) are used throughout the course and you will be advised to download and install these packages on your personal laptop computer.

Details of the recommended textbooks for this course are also provided in Part B of the course guide.

Overview of Assessment

Note that:

This course has no hurdle requirements.

Assessment Task 1: Assignment - Image enhancement in the spatial and frequency domains (Weighting 20%)

This assessment task supports CLOs 2, 3, 7, 8

Assessment Task 2: Assignment – Segmentation and Morphological Operations (Weighting 10%)

This assessment task supports CLOs 2, 3, 5, 7, 8

Assessment Task 3: Assignment – Spatial Transforms, 3D visualization, Registration (Weighting 20%)

This assessment task supports CLOs 2, 3, 5, 6, 7, 8

Assessment Task 4: Final Exam - (Weighting 50%)

This assessment task supports CLOs 1-4, 7, 8