Course Title: Advanced Laboratory Medicine

Part A: Course Overview

Course Title: Advanced Laboratory Medicine

Credit Points: 24.00


Course Code




Learning Mode

Teaching Period(s)


Bundoora Campus


173H School of Health and Biomed


Sem 2 2017

Course Coordinator: Prof Denise Jackson

Course Coordinator Phone: +61 3 9925 7392

Course Coordinator Email:

Course Coordinator Location: 201.09.013

Pre-requisite Courses and Assumed Knowledge and Capabilities

Enforced Pre-requisites: Advanced Laboratory Medicine-Haematology MEDS2112 Advanced Haematology; Advanced Laboratory Medicine-Transfusion and Transplantation Science ONPS2361 Advanced Transfusion and Transplantation Science; Advanced Laboratory Medicine-Cytopathology MEDS2135 Advanced Cytopathology; Advanced Laboratory Medicine-Histopathology MEDS2113 Advanced Histopathology; Advanced Laboratory Medicine-Clinical Biochemistry ONPS2342 Advanced Clinical Biochemistry; Advanced Laboratory Medicine-Medical Microbiology ONPS1045 Bacterial infections or ONPS1047 Pathogenesis of Enteric Infections or BIOL2401 Parasites and BIOL2402 Viruses and Infection.

Course Description

This capstone course has a vocational focus in a specific discipline of Laboratory Medicine. This course is taken as part of a major discipline stream in the final year of the program and is designed to equip graduates with the knowledge and skills to competently undertake investigations into a range of discipline specific diseases. A series of problem solving exercises examine the clinical presentation and laboratory investigation of a range of discipline specific diseases.
In addition, a laboratory based project will assist you to develop skills in biological research and scientific communication, including design and performance of experiments, analysis and presentation of experimental data, oral and written scientific reports that use these skills.

Objectives/Learning Outcomes/Capability Development

This course contributes to the following Program Learning Outcomes for MC158 Master of Laboratory Medicine degree program AQF9:

• PLO1. Knowledge capability: Have a comprehensive understanding of key scientific principles underpinning laboratory medicine and have developed a systemic knowledge of core cellular and molecular processes underlying health and disease. Have advanced knowledge of two core clinical speciality disciplines of laboratory medicine and advanced management skills,
• PLO2. Technical capability: Ability to develop and perform a range of diagnostic techniques relevant to the field of laboratory medicine. To use logical and systemic thinking and high level critical analysis skills to solve problems by utilising diagnostic techniques and methodologies in the chosen areas of clinical laboratory specialisation,
• PLO3. Professional work practices: Have a critical awareness of principles relating to scientific integrity, ethical issues and legal framework that underpins the field of laboratory medicine. Contribute to professional work settings through effective interpersonal and teamwork skills to support constructive interactions,
• PLO4. Communication skills: Ability to communicate effectively with individuals and groups within the diagnostic laboratory environment. Acquire, organise, critically analyse, interpret and present information to media in professional settings on current issues in laboratory medicine, and
• PLO6. Research capability: Ability to apply the principles and methods of scientific inquiry and research design to plan and perform hypothesis-driven research project in the field of laboratory medicine or an in-depth advanced professional practice in laboratory medicine work experience.


On completion of this course you should be able to:

• CLO1. Define at an advanced level the complex nature of events contributing to normal and abnormal disease states in your discipline.
• CLO2. Evaluate and perform laboratory techniques and instrumentation with respect to accuracy, precision, sensitivity and cross-reactivity.
• CLO3. Describe the clinical presentation of a variety of discipline based disorders.
• CLO4. Conduct an independent, laboratory-based investigative project.
• CLO5. Apply proper laboratory practice regarding data collection and recording, laboratory safety, time and project management, experimental design, accuracy and precision, analysis and interpretation of results.
• CLO6. Analyse and interpret scientific literature, experimental data, prepare a minor thesis (literature review, materials and methods, results, discussion and bibliography).
• CLO7. Report findings of a laboratory based project in an oral seminar.

Overview of Learning Activities

This is a discipline-based course from a major stream that is designed to prepare graduates for a career in laboratory medicine, or to pursue postgraduate research in the discipline. The syllabus is covered in a program of lectures, tutorials, laboratory based project and seminar. Tuition is primarily based on problem solving exercises which are designed to extend theoretical knowledge and to develop analytical and critical thinking skills.
Preparation of a reference list and project outline, project work under the guidance of a supervisor, participation in laboratory meetings, seminars, writing and editing a minor thesis in consultation with supervisor, preparation of and presentation of a seminar and a poster.

Total study hours: 10 hours per week (120 hours per semester face to face contact) including lecture (2 hours), 1 hour tutorial and 7 hours practical class. Students are expected to do equivalent hours of independent study each week around each of their assessment tasks and for active revision of their course.

Overview of Learning Resources

This course uses a combination of:
Practical manuals
Scientific journals
Internet based material/references
Lecture notes/supplementary material available via Online@RMIT
You should obtain material appropriate to your individual topic, by discussion with your supervisors and by searching the appropriate data bases and literature eg: PubMed.

Overview of Assessment

All hurdle requirements for this course are indicated clearly in the assessment regime that follows, against the relevant assessment task(s) and all have been approved by the College Deputy Pro Vice-Chancellor (Leaning & Teaching).

This course has hurdle requirements. Students need to Pass both the theory and practical project component to PASS this course.

Assessment tasks

Theory: 45%

Assessment Task 1: Final theory exam

Weighting 25%

This assessment task supports CLOs 1, 3, 5 & 6

Assessment Task 2: Assignments (Morphology or Case Reports or Quizzes depending upon discipline)

Weighting 20%

This assessment task supports CLOs 1 & 3

Practical Project: 55%

Assessment Task 3: Literature review

Weighting 10%

This assessment supports CLO 6

Assessment Task 4: Laboratory work (submission of lab notebook and supervisor assessment)

Weighting 10%

This assessment supports CLOs 2 & 5

Assessment Task 5: Final project report

Weighting 20%

This assessment supports CLOs 2, 4, 5 & 6

Assessment Task 6: Oral presentation

Weighting 15%

This assessment supports CLO 7

Marking rubrics are available for oral seminar, literature review, laboratory work and final project report. Formative feedback is given to all students during the semester with assignments, literature review and discipline based quizzes.