Course Title: Clinical Immunology

Part A: Course Overview

Course Title: Clinical Immunology

Credit Points: 12.00


Course Code




Learning Mode

Teaching Period(s)


Bundoora Campus


173H School of Health and Biomed


Sem 1 2017,
Sem 1 2018

Course Coordinator: Dr Dodie Pouniotis

Course Coordinator Phone: +61 3 9925 6680

Course Coordinator Email:

Course Coordinator Location: 201.10.010

Pre-requisite Courses and Assumed Knowledge and Capabilities


Course Description

This is a comprehensive introduction to the study of clinical immunology designed for undergraduate biomedical science students.

You will be introduced to basic immunological mechanisms including an overview of immunology, antigens and antibodies, cells of the immune system and soluble mediators of the immune system. Immune disorders including hypersensitivity reactions, autoimmune disorders, transplantation and tumour immunology will then be addressed. Students will also be given online video presentations from experts from medical/research institutions and diagnostic laboratories reviewing current topics in Clinical Immunology such as allergy, autoimmunity and immunotherapeutics.

Your subsequent study of Clinical Immunology will concentrate on the immunological methods used to evaluate human disease and include the theoretical basis for tests of immune function. You will develop basic skills necessary for clinical immunology testing in a diagnostic laboratory and apply critical thinking to solve clinical related questions,

You will develop a sound foundation for further study and professional practice in immunology and associated laboratories. The course requires you to integrate your knowledge of Immunology with other study areas including Anatomy, Physiology, Biochemistry and Genetics. It also provides a sound foundation for further study in Haematology, Blood Transfusion Science and Pathology.

Objectives/Learning Outcomes/Capability Development

This course contributes to the following Program Learning Outcomes for: 

MC158 Master of Laboratory Medicine 

  • PLO1. Have a comprehensive understanding of key scientific principles underpinning laboratory medicine and have developed a systemic knowledge of core cellular and molecular processes underlying health and disease. Have advanced knowledge of two core clinical speciality disciplines of laboratory medicine and advanced management skills.
  • PLO2. Technical capability: Ability to develop and perform a range of diagnostic techniques relevant to the field of laboratory medicine. To use logical and systemic thinking and high level critical analysis skills to solve problems by utilising diagnostic techniques and methodologies in the chosen areas of clinical laboratory specialisation.

On successful completion of this course you should be able to: 

  1. Describe the normal structure, function and regulation of the immune system.
  2. Describe how the immune system causes and prevents human disease.
  3. Explain the immunological basis of human disease as is applied in a diagnostic immunology laboratory as well as a research laboratory.
  4. Develop effective skills in problem-solving and self-directed learning to develop a greater depth of knowledge in Clinical Immunology.
  5. Perform basic and specific laboratory techniques related to diagnostic and clinical immunology.
  6. Apply diagnostic reasoning of current topics in Clinical Immunology and examine their importance in a clinical and research setting. to understanding disease states and their immunological causes through critical analysis of current literature and practice.

Overview of Learning Activities

The course will include a wide range of blended learning activities designed to stimulate your interest in the topics being covered. The theoretical and practical components of this course are highly integrated. Interactive lectures, active learning workshops, self-directed online learning activities, class discussions and feedback from learning activities will facilitate both group and independent learning. This includes lectures delivered face to face as well as online.

Integrated active learning workshops will involve various activities to consolidate lecture concepts and introduce clinical cases relevant to course content. Review and analysis of content presented by experts in the field of Clinical Immunology will be covered and assessed in these workshops. You will participate in engaging and relevant practical laboratory sessions where you will learn the techniques used in a contemporary Immunology laboratory. You will work both individually and also collaboratively with your peers and subject experts at the interface of theory, experimentation and application.

Over the semester, students will participate in 4-5 hours per week incorporating interactive lectures, practical workshops and online learning activities. In addition, you can expect to spend a minimum of 3 hours per week in independent study, including online work.

Overview of Learning Resources

Learning resources in this course include lecture notes, active learning workshop worksheets, laboratory notes and online learning material. All resources are made available via the RMIT online Learning Management System (LMS). Prescribed textbooks and recommended references are available in the library.

Other Resources

Please refer to the Resources Folder via the RMIT online Learning Management System (LMS).

Overview of Assessment

This course has no hurdle requirements.

On-going assessments tasks will be conducted during semester including in-class theory tests, workshop based assessments, practical post-lab tests and exam and a final theory exam.

The theory assessments during the semester will test your understanding of the components of the immune system, how they interact in the context of clinical cases. The practical assessments during the semester will test your understanding the underlying principles and procedures of diagnostic testing in clinical immunology and to apply critical thinking and problem-based learning techniques to apply basic immunologic information to selected clinical case studies

Assessment Tasks

Assessment Task 1: Mid-semester Test

Weighting 15%

This assessment task supports CLOs 1 & 2

Assessment Task 2: Active Learning Workshop Assessments

Weighting 20%

This assessment task supports CLOs 1, 2, 3, 4 & 6

Assessment Task 3: Online pre and post lab quizzes

Weighting 10%

This assessment task supports CLOs 3, 4 & 5

Assessment Task 4: Practical Exam

Weighting 25%

This assessment task supports CLOs 3, 4 & 5

Assessment Task 5: Final Theory Exam

Weighting 30%

This assessment supports CLOs 1, 2, & 3