Course Title: Biochemistry and Molecular Biology 2

Part A: Course Overview

Course Title: Biochemistry and Molecular Biology 2

Credit Points: 12.00


Terms

Course Code

Campus

Career

School

Learning Mode

Teaching Period(s)

BIOL1179

Bundoora Campus

Postgraduate

160H Medical Sciences

Face-to-Face

Sem 2 2006,
Sem 2 2007,
Sem 2 2008,
Sem 2 2009

BIOL1181

Bundoora Campus

Undergraduate

160H Medical Sciences

Face-to-Face

Sem 2 2006,
Sem 2 2007,
Sem 2 2008,
Sem 2 2009,
Sem 2 2010,
Sem 2 2011,
Sem 2 2012,
Sem 2 2013,
Sem 2 2014,
Sem 2 2015,
Sem 2 2016

BIOL1181

Bundoora Campus

Undergraduate

173H School of Health and Biomed

Face-to-Face

Sem 2 2017

Course Coordinator: Dr Daniel Dias

Course Coordinator Phone: +61 3 9925 7071

Course Coordinator Email: daniel.dias@rmit.edu.au

Course Coordinator Location: 201.09.014C

Course Coordinator Availability: By appointment


Pre-requisite Courses and Assumed Knowledge and Capabilities

Required prior study: Chemistry for Life Sciences (CHEM1240), Biology of the Cell (BIOL2272), Introduction to Medical Biochemistry (ONPS2423), or equivalent courses.  Assumed knowledge: BIOL1177 Biochemistry & Molecular Biology 1.


Course Description

Biochemistry and Molecular Biology 2 is a major component of the second year of the Laboratory Medicine (BP147), Biomedical Sciences (BP231) and Pharmaceutical Sciences (BP184) programs. This subject is designed to extend student theoretical and practical knowledge in the fields of Biochemistry, Molecular Biology, Clinical Biochemistry and Metabolomics, the latter which is an emerging multidisciplinary science, combining aspects of biology, analytical chemistry, experimental design and data interpretation.The theory you will learn throughout the course will be intertwined and applied into a series of intensive laboratory practicals throughout the semester.Through the course you will gain an immersive laboratory experience covering concepts of experimental design, sample preparation and learning about current, state-of-the-art analytical techniques and platforms which are routinely used in clinical practise and research. You will develop the required employable attributes to either undertake professional practice or potential research endeavours.


Objectives/Learning Outcomes/Capability Development

This course contributes to the following Program Learning Outcomes for:

BP147 Bachelor of Biomedical Science (Laboratory Medicine)

PLO1. Knowledge capability: Understand appropriate and relevant, theoretical concepts of scientific knowledge with the ability to use and apply the knowledge in a wide range of problem solving, challenging and interpretative situations within the professional laboratory medicine discipline.

PLO2. Technical capability: Ability to apply a range of diagnostic technologies and methodologies relevant to the fields of Clinical Biochemistry, Haematology, Histopathology, Cytopathology or Microbiology.  These methodologies will identify pathological changes which deviate from the normal physiological range, use logical and systematic thinking to solve problems with diagnostic techniques and procedures, and apply high level analytical skills to the chosen area of clinical laboratory specialization.

PLO3. Professional work practices: Contribute to academic and professional work settings through responsible, self-managed, independent work, interpersonal skills which support constructive interactions with individuals and teams, and understand the ethical and legal framework that underpins the field of diagnostic pathology.


 

BP184 Bachelor of Biomedical Science (Pharmaceutical Sciences)

PLO1. Exhibiting depth and breadth of scientific knowledge: Develop a broad and coherent body of knowledge particularly in biochemistry, physiology, pharmacology and toxicology. 

PLO2. Critically analyse and solve scientificproblems: Adapt knowledge, concepts and skills to problem solve.

 

BP231 Bachelor of Biomedical Science

PLO2. Exhibit depth and breadth of scientific knowledge by: Demonstrating knowledge across disciplines contributing to biomedical science 

PLO3. Critically analyse and solve scientific problems by: Gathering, synthesising and critically evaluating information from a range of sources; Designing and planning an investigation; Selecting and applying practical and/or theoretical techniques or tools in order to conduct an investigation and collecting, accurately recording, interpreting and drawing conclusions from scientific data.


On completion of this course you should:

  1. Be able to demonstrate an understanding of key concepts in biochemistry and molecular biology which will form a comprehensive basis for further studies in the majors of either Biochemistry, Molecular Biology, Metabolomics and Clinical Biochemistry. 
  2. Be able to demonstrate an understanding of key concepts in human biochemistry and molecular biology which will form a basis for further studies in other major courses offered in the Laboratory Medicine program, Biomedical Sciences program, Pharmaceutical Science program and other programs offered by the College of Science, Engineering and Technology.
  3. Be able to prepare and analyse biological material for biochemical investigation. 
  4. Be able to correlate, validate and interpret results of biochemical investigations.


Overview of Learning Activities

The learning activities of the course take place in the form of face-to-face lectures; laboratory based practical classes and tutorial sessions. The theory and practical components of the course are integrated throughout the teaching of the course. The practical program is designed to develop a high level of competence in the performance of a wide range of laboratory techniques.

A student-centered approach is adopted in the tutorial sessions and the self-directed learning activities of the course. These activities are conducted in parallel with the lecture program and consist of

  • Targeted student-based discussions and;
  • Problem-solving of specific case studies and/or experimental data interpretation

Assessment activities are conducted as both formative and summative assessments. Formative as well as summative assessment occurs throughout the teaching in the laboratory classes of the course. Tutorials and self-directed learning activities;  Interactive, real-time quizzes at the end of selected lectures will provide continuous feedback to the student and lecturer regarding his/her understanding and level of performance in the interpretation of biochemical concepts and manipulation of biochemical data. Students will be able to access resources (eg. Lecture notes and recorded lectures, supplementary data) through the RMIT’s Blackboard Learning Management System which is the central forum used to communicate announcements and discuss questions with academics and peers.


Overview of Learning Resources

Learning resources in this course include text books, lecture notes (Powerpoint presentations), laboratory practical exercises, real-time quizzes, handouts and references on selected topics. The myRMIT site provides opportunities for students to independently access much of this material and use an asynchronous conference.


Overview of Assessment

This course has no hurdle requirements.

In order to satisfactorily complete the course, all students are required to undertake at least 80% of the practical work and to obtain an overall Pass for the Practical component of the course. Students must note that the laboratory sessions are available only at the specified times. The theoretical component of the course delivered in lectures will be assessed in a final semester examination, as well as two (2) Mid semester tests.

Assessment Tasks

Assessment Task 1: Laboratory Practicals

Weighting 30%

This assessment task supports 3 & 4

Assessment Task 2: Mid-Semester Test 1 (DNA Technologies, Hormones and Biosignaling)

Weighting 10%

This assessment task supports 1 & 2

Assessment Task 3: Mid-Semester Test 2 (Metabolism)

Weighting 10%

This assessment task supports 1 & 2

Assessment Task 4: Final Examination

Weighting 50%

This assessment task supports 1, 2 & 4