Course Title: Clinical Biochemistry 1

Part A: Course Overview

Course Title: Clinical Biochemistry 1

Credit Points: 12.00


Course Code




Learning Mode

Teaching Period(s)


Bundoora Campus


160H Medical Sciences


Sem 2 2006,
Sem 2 2007,
Sem 2 2008,
Sem 2 2009,
Sem 2 2010,
Sem 2 2011,
Sem 2 2012,
Sem 2 2013,
Sem 2 2014,
Sem 2 2015,
Sem 2 2016


Bundoora Campus


173H School of Health and Biomed


Sem 2 2017

Course Coordinator: Dr Daniel Dias

Course Coordinator Phone: +61 3 9925 7071

Course Coordinator Email:

Course Coordinator Location: 201.09.014C

Course Coordinator Availability: By appointment and via email

Pre-requisite Courses and Assumed Knowledge and Capabilities

Required prior study: Chemistry for Life Sciences (CHEM1240), Biology of the Cell (BIOL2272), Introduction to Medical Biochemistry (ONPS2423), or equivalent courses.  Assumed knowledge:  Biochemistry and Molecular Biology 1 (BIOL1177).

Course Description

Clinical Biochemistry 1 is an elective subject for Master of Laboratory Medicine (MC158) and Master of Biotechnology (MC111).This subject is designed to extend your theoretical and practical knowledge in the fields of Biochemistry, Molecular Biology, Clinical Biochemistry and Metabolomics, the latter which is an emerging multidisciplinary science, combining aspects of biology, analytical chemistry, experimental design and data interpretation.The theory you will learn throughout the course will be intertwined and applied into a series of intensive laboratory practicals throughout the semester.Through the course you will gain an immersive laboratory experience covering concepts of experimental design, sample preparation and learning about current, state-of-the-art analytical techniques and platforms which are routinely used in clinical practise and research. You will develop the required employable attributes to either undertake professional practice or potential research endeavours.

Objectives/Learning Outcomes/Capability Development

  • This course contributes to the following Program Learning Outcomes for:

    MC158 Master of Laboratory Medicine

    PLO1.  Knowledge capability: Have a comprehensive understanding of key scientific principles underpinning laboratory medicine and have developed a systemic knowledge of core cellular and molecular processes underlying health and disease.  Have advanced knowledge of two core clinical speciality disciplines of laboratory medicine and advanced management skills. 

    PLO2. Technical capability: Ability to develop and perform a range of diagnostic techniques relevant to the field of laboratory medicine.  To use logical and systemic thinking and high level critical analysis skills to solve problems by utilising diagnostic techniques and methodologies in the chosen areas of clinical laboratory specialisation.


    MC111 Master of Biotechnology

    PLO1. Understanding science: You will demonstrate an advanced understanding of biological sciences by articulating the methods of science, explaining why current biological knowledge is both contestable and testable through further inquiry, and explaining the role and relevance of biotechnology in society; You will have an understanding of recent developments in a specialised area of biotechnology; You will demonstrate knowledge of research principles and methods applicable to biological sciences.

     PLO2. Advanced skills to critically analyse and solve problems in biotechnology: You will demonstrate cognitive skills in mastery of advanced theoretical knowledge in biotechnology and apply this knowledge to solve complex problems in existing and new areas; You will generate and evaluate complex ideas and concepts at an abstract level.


On completion of this course you should be able to:

  1. Relate key concepts in biochemistry and molecular biology to applications in  biochemistry, molecular biology, metabolomics and clinical biochemistry. CLO1.
  2. Relate key concepts in human biochemistry and molecular biology to applications in laboratory medicine, biomedical sciences program or pharmaceutical sciences. CLO2.
  3. Prepare and analyse biological material for biochemical investigation. CLO3. 
  4. Correlate, validate and interpret results of biochemical investigations. CLO4.

Overview of Learning Activities

The learning activities of the course take place in the form of face-to-face lectures; laboratory based practical classes and tutorial sessions. The theory and practical components of the course are integrated throughout the teaching of the course. The practical program is designed to develop a high level of competence in the performance of a wide range of laboratory techniques.

A student-centered approach is adopted in the tutorial sessions and the self-directed learning activities of the course. These activities are conducted in parallel with the lecture program and consist of

  • Targeted student-based discussions and;
  • Problem-solving of specific case studies and/or experimental data interpretation

Assessment activities are conducted as both formative and summative assessments. Formative as well as summative assessment occurs throughout the teaching in the laboratory classes of the course. Tutorials and self-directed learning activities;  Interactive, real-time quizzes at the end of selected lectures will provide continuous feedback to the student and lecturer regarding his/her understanding and level of performance in the interpretation of biochemical concepts and manipulation of biochemical data. Students will be able to access resources (eg. Lecture notes and recorded lectures, supplementary data) through the RMIT’s Blackboard Learning Management System which is the central forum used to communicate announcements and discuss questions with academics and peers.


Assessment activities are conducted as both formative and summative assessments. Formative as well as summative assessment occurs throughout the teaching in the laboratory classes of the course. You will undertake 3 hours of lectures per week (34 hours in total); 5 hours of tutorials consisting of self-directed learning; 24 hours of laboratory practical classes consisting of both wet and dry based practicals which are all face-to-face based. It is expected that you will carry out a total of 64 hours of independent study for this course throughout the semester.

Overview of Learning Resources

Learning resources in this course include text books, lecture notes (Powerpoint presentations), laboratory practical exercises, real-time quizzes, handouts and references on selected topics. The myRMIT site provides opportunities for students to independently access much of this material and use an asynchronous conference.

Overview of Assessment

This course has no hurdle requirements.

In order to satisfactorily complete the course, all students are required to undertake at least 80% of the practical work and to obtain an overall Pass for the Practical component of the course. Students must note that the laboratory sessions are available only at the specified times. The theoretical component of the course delivered in lectures will be assessed in a final semester examination, as well as two (2) Mid semester tests.

Assessment Tasks 

Assessment Task 1: Laboratory Practicals

Weighting 30%

This assessment task supports 3 & 4

Assessment Task 2: Mid-Semester Test 1 (DNA Technologies, Hormones and Biosignaling)

Weighting 10%

This assessment task supports 1 & 2

Assessment Task 3: Mid-Semester Test 2 (Metabolism)

Weighting 10%

This assessment task supports 1 & 2

Assessment Task 4: Final Examination

Weighting 50%

This assessment task supports 1, 2 & 4