Course Title: Biology of Tissue Growth and Repair

Part A: Course Overview

Course Title: Biology of Tissue Growth and Repair

Credit Points: 12.00


Course Code




Learning Mode

Teaching Period(s)


Bundoora Campus


160H Medical Sciences


Sem 2 2006,
Sem 2 2007,
Sem 2 2008,
Sem 2 2009,
Sem 2 2010,
Sem 2 2011,
Sem 2 2012,
Sem 2 2013,
Sem 2 2014,
Sem 2 2015,
Sem 2 2016


Bundoora Campus


173H School of Health and Biomed


Sem 2 2018,
Sem 2 2019,
Sem 2 2020,
Sem 2 2021,
Sem 2 2022,
Sem 2 2023


Bundoora Campus


160H Medical Sciences


Sem 2 2006,
Sem 2 2007,
Sem 2 2008,
Sem 2 2009,
Sem 2 2010

Course Coordinator: A/Prof Terry Piva

Course Coordinator Phone: +61 3 9925 6503

Course Coordinator Email:

Course Coordinator Location: 201.09.006

Pre-requisite Courses and Assumed Knowledge and Capabilities

Required prior study (Pre-requisites)

Course Description

This course through a series of lectures, tutorials and practicals highlights the current understanding of cellular mechanisms involved in processes such as cell growth and differentiation, cell proliferation and death and their importance in health and disease processes. Emphasis in the lecture component of the course will be on understanding the processes involved and how these relate to diseases such as inflammation and cancer. In the practical component students will study advanced cell biological methods that are currently employed in research and diagnostic laboratories. Analysis of research material will develop the students’ critical thinking in current aspects of tissue dynamics and interactions. The skills developed will be of importance in future study as postgraduate students or employment in research laboratories or industry.

You will gain knowledge in the processes of tissue repair and pathological processes such as inflammation and wound repair, immune system function, cancer development, tumour immunology, skin biology, and stem cells. The practical component will extend your laboratory skills in the area of cell biology techniques such as flow cytometry and cell sorting, western blotting, cell migration.

Objectives/Learning Outcomes/Capability Development

This course contributes to the program learning outcomes in the following disciplines:

Biomedical Science (BP231):

  • Scientific knowledge (PLO 2)
  • Inquiry and problem solving (PLO 3)
  • Communication skills (PLO 4)

Biotechnology/Biomedical Science (BP293):

  • Exhibit depth and breadth of scientific knowledge (PLO 2)
  • Critically analyse and solve scientific problems (PLO 3)

Upon successful completion of this course, you will be able to:

  1. Explain the processes involved in normal cell growth, adult tissue and stem cells to analyse the effect of disease on these processes.
  2. Differentiate the roles played by oncogenes and tumor suppressor genes in tumorigenesis;
  3. Discuss the effect altered signalling pathways play in tumour cells;
  4. Evaluate the role played by stromal cells in cancer cell biology;
  5. Identify the protective roles epidermal cells play in skin biology;
  6. Distinguish between immune system function in both normal and diseased patients;
  7. Evaluate the mechanisms involved in boosting immune system function in cancer patients;
  8. Retrieve and present relevant literature in regards to tumorigenesis, tumour immunology, wound repair and immune system dysfunction.

Overview of Learning Activities

Recorded lectures will introduce you to the latest understanding of tissue growth, repair and the factors controlling cell differentiation, proliferation and death. The basis of the techniques used to study these processes will be examined in lectures and tutorials and you will then be able to use some of these techniques in practical classes.

The practical component will include an introduction to techniques used for studying immune cell function, cell growth and tissue repair, including cell signalling, cell migration and in vitro models of fibroblast and endothelial cell growth and differentiation.

Tutorials are used to discuss the current literature in the areas of immune cell function, cell growth and differentiation and important concepts in the area of repair such as fibrosis, angiogenesis, stem cells as well as cancer development, metastasis and current treatment therapies. Tutorials are designed to assist students in their understanding of material delivered in lectures.

The assignment will be based on current developments in areas of tissue growth and repair as presented in the lectures. This will develop the student’s ability to undertake a research of scientific literature, and will develop their ability to write a report based on this work.

Overview of Learning Resources

RMIT will provide you with resources and tools for learning in this course through myRMIT Studies Course.

There are services available to support your learning through the University Library. The Library provides guides on academic referencing and subject specialist help as well as a range of study support services. For further information, please visit the Library page on the RMIT University website and the myRMIT student portal.

Overview of Assessment

This course has no hurdle requirements.

Assessment Tasks

Assessment Task 1: Practical reports (4)
Weighting 20%
This assessment task supports CLOs 1, 3, 5, 6, 7 & 8

Assessment Task 2: Quizzes (6)
Weighting 20%
This assessment task supports CLOs 1, 2, 3 & 4

Assessment Task 3: Written Assignment  

Weighting 20%
This assessment task supports CLOs 1, 2, 3, 4, 5, 6 & 7

Assessment Task 4: Final in class test
Weighting 40%
This assessment task supports CLOs 1, 2, 3, 4, 5, 6 & 7