Course Title: Clinical Immunology

Part A: Course Overview

Course Title: Clinical Immunology

Credit Points: 12.00


Course Code




Learning Mode

Teaching Period(s)


Bundoora Campus


173H School of Health and Biomed


Sem 1 2017,
Sem 1 2018,
Sem 1 2019,
Sem 1 2020

Course Coordinator: Dodie Pouniotis

Course Coordinator Phone: +61 3 9925 6680

Course Coordinator Email:

Course Coordinator Location: 201.10.010

Pre-requisite Courses and Assumed Knowledge and Capabilities


Course Description

This is a comprehensive introduction to the study of clinical immunology designed for undergraduate biomedical science students.

You will be introduced to basic immunological mechanisms including an overview of immunology, antigens and antibodies, cells of the immune system and soluble mediators of the immune system. Immune disorders including hypersensitivity reactions, autoimmune disorders, transplantation and tumour immunology will then be addressed. 

Your subsequent study of Clinical Immunology will concentrate on the immunological methods used to evaluate human disease and include the theoretical basis for tests of immune function. You will develop basic skills necessary for clinical immunology testing in a diagnostic laboratory and apply critical thinking to solve clinical related questions.

You will develop a sound foundation for further study and professional practice in immunology and associated laboratories. The course requires you to integrate your knowledge of Immunology with other study areas including Anatomy, Physiology, Biochemistry and Genetics. It also provides a sound foundation for further study in Haematology, Blood Transfusion Science and Pathology.

Objectives/Learning Outcomes/Capability Development

This course contributes to the following Program Learning Outcomes for: 

BP147 Bachelor of Biomedical Science (Laboratory Medicine) 

  • PLO 1. Knowledge capability: Understand appropriate and relevant, theoretical concepts of scientific knowledge with the ability to use and apply the knowledge in a wide range of problem solving, challenging and interpretative situations within the professional laboratory medicine discipline.
  • PLO 2. Technical capability: Ability to apply a range of diagnostic technologies and methodologies relevant to the fields of Clinical Biochemistry, Haematology, Histopathology, Cytopathology or Microbiology. These methodologies will identify pathological changes which deviate from the normal physiological range. Students will use logical and systematic thinking to solve problems with diagnostic techniques and procedures, and apply high level analytical skills to the chosen area of clinical laboratory specialisation.
  • PLO 3. Professional practices: Contribute to academic and professional work settings through responsible, self- managed, independent work, interpersonal skills which support constructive interactions with individuals and teams, and understand the ethical and legal framework that underpins the field of diagnostic pathology. 

BP231 Bachelor of Biomedical Science 

  • PLO 2. Exhibit depth and breadth of scientific knowledge by:

2.1 Demonstrating knowledge across disciplines contributing to biotechnology and biomedical science.

  • PLO 3. Critically analyse and solve scientific problems by:

3.3 Selecting and applying practical and/or theoretical techniques or tools in order to conduct an investigation.

On successful completion of this course you should be able to: 

  1. Explain the normal structure, function and regulation of the immune system and describe how it may cause and prevent disease.
  2. Evaluate the immunological basis of human disease and its diagnosis in a professional laboratory.
  3. Analyse and demonstrate effective skills in problem-solving through written and verbal communication to a professional and non-professional audience.
  4. Competently perform basic and specific laboratory techniques related to human disease relevant within a global context.


Overview of Learning Activities

The course will include a wide range of blended learning activities designed to stimulate your interest in the topics being covered. This includes lectures delivered face to face as well as online. Integrated active learning workshops will involve various activities to consolidate lecture concepts and introduce clinical cases relevant to course content.

Industry experts will present authentic and current topics direct from the field. You will participate in engaging and relevant practical laboratory sessions where you will learn the techniques used in a contemporary Immunology laboratory. You will work both individually and also collaboratively with your peers and subject experts at the interface of theory, experimentation and application.

You will undertake 5 hours per week in lectures, online videos, active learning workshops and intensive laboratory practical sessions. In addition, you can expect to spend a minimum of four hours per week in independent study, including online work.

Overview of Learning Resources

Learning resources in this course include lecture notes, active learning workshop worksheets, laboratory notes and online learning material. All resources are made available via the RMIT online Learning Management System (LMS). Prescribed textbooks and recommended references are available in the library.

Other resources
Please refer to the Resources Folder via the RMIT online Learning Management System (LMS).

Overview of Assessment

This course has no hurdle requirements. 

On-going assessments tasks will be conducted during semester including active learning workshops, in-class theory tests, practical assessments and a final theory exam.

The theory assessments during the semester will test your understanding of the components of the immune system, how they interact in the context of clinical cases. The practical assessments during the semester will test your understanding the underlying principles and procedures of diagnostic testing in clinical immunology and to apply critical thinking and problem-based learning techniques to apply basic immunologic information to selected clinical case studies.

Assessment Tasks

Assessment Task 1: Mid-semester test

Weighting 15%

This assessment task supports CLOs 1 & 3

Assessment Task 2: Active Learning Workshop Assessments

Weighting 20%

This assessment task supports CLOs 1, 2 & 3 

Assessment Task 3: Practical Assessment

Weighting 35%

This assessment task supports CLOs 1, 2, 3 & 4

Assessment Task 4: Final Theory Exam

Weighting 30%

This assessment task supports CLOs 1 & 3