Course Title: Systems Biology

Part A: Course Overview

Course Title: Systems Biology

Credit Points: 12.00

Important Information:

To participate in any RMIT course in-person activities or assessment, you will need to comply with RMIT vaccination requirements which are applicable during the duration of the course. This RMIT requirement includes being vaccinated against COVID-19 or holding a valid medical exemption. 

Please read this RMIT Enrolment Procedure as it has important information regarding COVID vaccination and your study at RMIT: https://policies.rmit.edu.au/document/view.php?id=209. 

Please read the Student website for additional requirements of in-person attendance: https://www.rmit.edu.au/covid/coming-to-campus 

Please check your Canvas course shell closer to when the course starts to see if this course requires mandatory in-person attendance. The delivery method of the course might have to change quickly in response to changes in the local state/national directive regarding in-person course attendance.


Terms

Course Code

Campus

Career

School

Learning Mode

Teaching Period(s)

BIOL2512

City Campus

Undergraduate

171H School of Science

Face-to-Face

Sem 1 2021,
Sem 1 2022

Course Coordinator: Kylie Boyce

Course Coordinator Phone: +61 3 9925 7101

Course Coordinator Email: kylie.boyce@rmit.edu.au

Course Coordinator Location: 223.01.006G


Pre-requisite Courses and Assumed Knowledge and Capabilities

Prior background in molecular and cell biology.


Course Description

This course focuses on developing understanding of the Systems Biology approach, whereby biological systems are studied from the level of molecules to populations, via multi-omics approach.  

Lectures building on the fundamentals of molecular and cell biology will demonstrate and illustrate how an integrated suite of genomics, transcriptomics, proteomics, metabolomics and bioinformatics tools can be deployed to understand how the structure, function and activity of biological systems from cells to tissues to individual organisms and to populations and in turn how intra and inter-cellular (including environmental) signals influences the genetics, gene expression and translation within organisms and ultimately their biological function.  

Theoretical background will be supplemented by laboratory sessions introducing you to the generation and analysis of Omics datasets from model organisms.  

The course will develop your advanced level critical thinking, problem solving and (scientific) communication skills and their application to describe, explain and interrogate complex biological systems. This will provide you with detailed understanding and the necessary skills to analyse complex biological processes and systems within the context of biology and biotechnology, either in industry or in a research environment.


Objectives/Learning Outcomes/Capability Development

This course contributes to the BP226 Bachelor of Science (Biotechnology) Program Learning Outcomes:

  • 2.1 You will demonstrate cognitive skills in mastery of advanced theoretical knowledge in biotechnology and apply this knowledge to solve complex problems in existing and new areas.
  • 3.2. You will exhibit depth and breadth of knowledge by demonstrating that biotechnology has interdisciplinary connections with other sciences.
  • 3.6. You will be able to critically analyse and solve problems in biotechnology by collecting, accurately recording, interpreting, and drawing conclusions from scientific data.
  • 4.1. You will be an effective communicator of biological sciences by effectively communicating scientific results, information, or arguments using a range of modes (oral, written, visual) for a variety of purposes and audiences.
  • 5.2. You will be accountable for  individual learning and scientific work by working effectively, responsibly, ethically, and safely in an individual or team context.


On the successful completion of this course, you should be able to:

  1. Demonstrate theoretical and technical understanding of Systems Biology (Omics) approaches to the study of biological systems from the levels of molecules to cells, tissues, organisms and populations.
  2. Critically analyse, interpret and explain omics data.
  3. Summarise and synthesize and evaluate primary scientific literature.
  4. Communicate clearly and effectively using correct scientific language and conventions.


Overview of Learning Activities

You will learn in this course by:

  • studying learning from lectures and participation in tutorials where theoretical material will be introduced, including discussion and exploration of key research literature;
  • undertake laboratory activities designed to provide practical application and analysis of omics methods and resulting datasets
  • completion of written assignments focusing on the analysis, presentation and discussion of biological omics data requiring application of theoretical knowledge to experimental data
  • private study, working through the course as presented in classes and learning materials, and gaining practice at solving conceptual and numerical problems.


Overview of Learning Resources

There are no prescribed text or recommended books for this course. Students should obtain material appropriate to their individual topic and by searching appropriate data bases e.g. Scopus, Web of Science, Google Scholar, Current Contents, PubMed etc.


Overview of Assessment

This course has no hurdle requirements.

Assessment Tasks 

Assessment Task 1:  Literature Review Assignment

Weighting 30%

This assessment task supports CLOs 1, 2, 3 & 4

Assessment Task 2: Journal Club Assignment

Weighting 20%

This assessment task supports CLOs 1, 2, 3 & 4

Assessment Task 3: Formative Assessment (quizzes and short answer questions)

Weighting 15%

This assessment task supports CLOs 1, 2, 3 & 4

Assessment Task 4: Practical Assessments

Weighting 35%

This assessment task supports CLOs 1, 2 ,3 & 4